Planet Skincare | Clinical Trials

Efficacy Tests | In vitro tests:

The efficacy of the SYN-AKE™ tripeptide (at a concentration of 0.5mM) has been demonstrated in vitro by measuring the frequency of contraction of the innervated muscle cell as a function of the incubation time.

SYN-AKE™ peptide reduces muscle cell contraction and its action if reversible.

Efficacy Tests | In vivi tests:

The measurement of the smoothing and anti-wrinkle effect of SYN-AKE™ (4%) was compared to a placebo. A cream was applied to the forehead twice daily during 28 days.

SYN-AKE™ - Age Killing Effect.

The smoothing effect (Ra) was measured on 80% of the volunteers and the anti-wrinkle effect (Rz, Rt) measured on 73% of the volunteers.

Results showed up to 52% of wrinkle size after 28 days application!

Conclusions

• SYN-AKE™ is an excellent anti-wrinkle active compound with a snake
  venom-like mode of activity
• SYN-AKE™ smoothes mimic wrinkles in a short period.
• SYN-AKE™ age killing effect particularly effective against expression lines
• SYN-AKE™ is an intensive anti-wrinkle care.
• SYN-AKE™ is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of waglerin 1, a peptide that is found in the venom of the Temple Viper, Tropidolaemus wagleri.